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Lymphocyte Immunization Therapy in Indore: Facts Before You Decide

LIT is promoted for recurrent miscarriage, but evidence does not support routine use. Learn what LIT is, what guidelines say and proven alternatives.

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Lymphocyte immunisation therapy (LIT) involves injecting a woman with white blood cells from her partner or a donor, based on the idea that it may change the immune response in pregnancy. It has been promoted for recurrent miscarriage and repeated IVF failure. At Asian Navkar Hospital, Indore, we believe you deserve clear, evidence-based information before considering any treatment, and this page explains what current research says.

What Do Guidelines Say?

International guidance, including the ESHRE guideline on recurrent pregnancy loss, recommends against using LIT for recurrent miscarriage, because good-quality studies have not shown that it increases live births. It also carries potential risks, such as transmission of infections and allergic or immune reactions.

Proven Steps for Recurrent Miscarriage

Before considering any immune therapy, couples should have a full recurrent miscarriage evaluation: antiphospholipid antibodies, thyroid function, uterine assessment, karyotype where indicated and lifestyle review. Treatments with evidence, such as aspirin and heparin for antiphospholipid syndrome or surgery for a uterine septum, are offered when the cause is found.

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If you have been advised LIT elsewhere or are considering it, our specialists can review your history and reports and explain all options, including supportive early pregnancy care, which itself helps many couples.

Why Families Choose Asian Navkar Hospital, Indore

  • Fertility, embryology, high-risk obstetrics and a Level 3 NICU in one hospital, so care continues after a positive pregnancy test.
  • Senior IVF team with 30+ years of clinical experience, including clinical embryologists.
  • Counselling for both partners, transparent written estimates and cashless TPA/insurance desk support where policies allow.

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Medical References

This page is for general information and does not replace a consultation. Treatment decisions are made only after an in-person evaluation by a qualified doctor at Asian Navkar Hospital, Indore.

Specialized Immune Evaluation
Careful assessment before considering this therapy.
Selectively Recommended
Used only in specific, evaluated cases.
Coordinated With Fertility Team
Integrated into your broader treatment plan.
Follow-Up Monitoring
Close monitoring throughout the treatment process.

Is this for you?

✓ Recurrent implantation failure with suspected immune factors ✓ Recurrent pregnancy loss after other causes ruled out ✓ Specific immunological test findings

How We Treat Lymphocyte Immunization Therapy (LIT)

1
Immunological Evaluation
Detailed testing to assess suitability for LIT.
2
Specialist Discussion
Reviewing potential benefits and considerations.
3
Treatment Administration
Therapy administered under medical supervision.
4
Follow-Up Assessment
Monitoring response before proceeding with treatment cycle.

Frequently Asked Questions

Current evidence does not show that LIT increases live birth rates, and major guidelines advise against it.

Because it uses blood cells from another person, there are risks such as infections and immune reactions.

A complete recurrent miscarriage evaluation and evidence-based treatment of any cause found.

Yes. Many women with unexplained recurrent miscarriage have a successful pregnancy with supportive care.

Do not stop prescribed medicines suddenly; discuss with your doctor first.

Dr. Vedant Jain
Dr. Vedant Jain
MBBS, MS (Obs & Gynae), DNB • Consultant IVF Specialist, Gynecologist & Embryologist
Reg. No. MP-37997 (MP Medical Council)

Dr. Vedant Jain is an IVF Consultant, Gynecologist, and Certified Embryologist at Asian Navkar Hospital, Indore. Holding post-graduate degrees including an MS and DNB in Obstetrics and Gynecology, he practises reproductive medicine at Asian Navkar Hospital. Dr. Jain specializes in advanced Assisted Reproductive Technologies (ART), complex infertility assessments, low AMH (ovarian reserve) optimization, and fertility preservation. By combining clinical gynecology with laboratory embryology, he works with couples who have had unsuccessful IVF cycles to plan further evaluation and treatment.

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