Recurrent Miscarriage Treatment in Indore
Had two or more miscarriages? Learn the causes, the tests that actually help, proven treatments and how we support your next pregnancy with close monitoring.
Losing a pregnancy is heartbreaking, and losing more than one can leave couples anxious and full of questions. Recurrent pregnancy loss (RPL) is usually defined as two or more pregnancy losses before 20–24 weeks. The encouraging fact is that many couples with RPL go on to have a successful pregnancy, often with careful evaluation, proven treatment where a cause is found, and supportive early pregnancy care. At Asian Navkar Hospital, Indore, we follow evidence-based guidance so that you get the tests that matter and avoid unproven treatments.
Common Causes of Recurrent Miscarriage
- Chromosomal problems in the embryo – the most common cause of individual miscarriages, more frequent with increasing age
- Parental chromosomal rearrangements – such as balanced translocations in either partner
- Antiphospholipid syndrome (APS) – an autoimmune condition that affects blood clotting in the placenta
- Uterine abnormalities – septate uterus, fibroids distorting the cavity, polyps or scarring (Asherman syndrome)
- Hormonal and metabolic conditions – uncontrolled thyroid disease, poorly controlled diabetes, PCOS
- Lifestyle factors – smoking, heavy alcohol use, obesity
In about half of couples, no clear cause is found even after full testing. This is called unexplained RPL, and the chance of a future successful pregnancy is still good.
Tests We Recommend
Testing follows international guidance such as the ESHRE recurrent pregnancy loss guideline:
- Antiphospholipid antibodies (lupus anticoagulant, anticardiolipin, anti-β2 glycoprotein I), repeated after 12 weeks if positive
- Thyroid function (TSH) and thyroid antibodies
- 3D ultrasound, sonohysterography or hysteroscopy to assess the uterine cavity
- Karyotype of pregnancy tissue where available; parental karyotype in selected cases
- Diabetes screening (HbA1c) and other tests based on your history
We usually do not recommend tests with little proven value, such as routine NK cell testing, HLA typing or extensive thrombophilia panels without an indication.
Treatment Options
- APS: low-dose aspirin with heparin injections during pregnancy, under close supervision
- Uterine septum, polyps or adhesions: corrected by hysteroscopic surgery
- Thyroid problems: thyroid medicine adjusted before and during pregnancy
- Parental translocation: genetic counselling, with PGT-SR discussed as one option
- Progesterone: may be advised for women with previous miscarriage who have bleeding in early pregnancy
- Lifestyle support: weight optimisation, stopping smoking and folic acid
Treatments That Are Not Recommended
Several treatments are promoted for RPL without good evidence of benefit. International guidelines advise against routine use of lymphocyte immunisation therapy (LIT), intravenous immunoglobulin, intralipids and steroids for unexplained RPL outside research settings. We explain the evidence clearly so you can make an informed choice.
Supportive Care in Your Next Pregnancy
Couples with RPL benefit from early and reassuring care. At Asian Navkar Hospital we offer early pregnancy scans, a direct contact number for concerns, emotional support and counselling. Once the pregnancy progresses, care continues with our high-risk pregnancy and fetal medicine teams.
Why Families Choose Asian Navkar Hospital, Indore
- Fertility, embryology, high-risk obstetrics and a Level 3 NICU in one hospital, so care continues after a positive pregnancy test.
- Senior IVF team with 30+ years of clinical experience, including clinical embryologists.
- Counselling for both partners, transparent written estimates and cashless TPA/insurance desk support where policies allow.
Related Services
- Genetic Counselling in Indore for Couples and Families
- PGT-SR in Indore
- High-Risk Pregnancy Doctor in Indore
- Prenatal Care in Indore
- Lymphocyte Immunization Therapy in Indore
Medical References
- ESHRE guidelines
- NHS - Miscarriage
- WHO - Maternal mortality fact sheet
- FOGSI - Federation of Obstetric & Gynaecological Societies of India
This page is for general information and does not replace a consultation. Treatment decisions are made only after an in-person evaluation by a qualified doctor at Asian Navkar Hospital, Indore.
Is this for you?
How We Treat Recurrent Pregnancy Loss (RPL)
Frequently Asked Questions
Most current guidelines, including ESHRE, define recurrent pregnancy loss as two or more pregnancy losses. Evaluation can be started after two losses.
Everyday activities, work, lifting normal objects, travel or mild stress do not cause miscarriage. Most early losses are due to chromosomal problems in the embryo.
Yes. Many couples with recurrent miscarriage, including those with no cause found, go on to have a successful pregnancy with supportive care.
PGT-A is not routinely recommended for unexplained RPL, as it has not been shown to increase live birth rates for most couples. It may be discussed in specific situations.
Heparin with aspirin is recommended for confirmed antiphospholipid syndrome. It is not routinely recommended for unexplained recurrent miscarriage.
Contact us as soon as your pregnancy test is positive. We usually plan an early scan at around 6–7 weeks.
Dr. Vedant Jain is an IVF Consultant, Gynecologist, and Certified Embryologist at Asian Navkar Hospital, Indore. Holding post-graduate degrees including an MS and DNB in Obstetrics and Gynecology, he practises reproductive medicine at Asian Navkar Hospital. Dr. Jain specializes in advanced Assisted Reproductive Technologies (ART), complex infertility assessments, low AMH (ovarian reserve) optimization, and fertility preservation. By combining clinical gynecology with laboratory embryology, he works with couples who have had unsuccessful IVF cycles to plan further evaluation and treatment.
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