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CHROMOSOMAL STRUCTURE SCREENING

PGT-SR in Indore: Embryo Testing for Chromosomal Rearrangements

Carry a balanced translocation or inversion? PGT-SR tests IVF embryos for unbalanced chromosomes to lower miscarriage risk. Know who needs it and the steps.

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Some healthy people carry a balanced chromosomal rearrangement, such as a translocation or inversion, without knowing it. It often comes to light after recurrent miscarriages or a child with a chromosomal condition. PGT-SR tests embryos to find those with a balanced or normal chromosome set. At Asian Navkar Hospital, Indore, PGT-SR is offered after detailed genetic counselling.

Who Should Consider PGT-SR?

Couples where one partner has a confirmed balanced translocation (reciprocal or Robertsonian) or inversion on karyotype, especially after recurrent miscarriage.

Your Options

Many carriers will eventually have a healthy pregnancy naturally, though with a higher miscarriage risk. PGT-SR with IVF is one option; others include natural conception with prenatal testing, or donor gametes. Genetic counselling helps you compare these choices.

The Process

IVF with ICSI, biopsy of blastocysts, freezing, laboratory analysis and transfer of an embryo without an unbalanced rearrangement in a later frozen cycle. Prenatal confirmation in pregnancy is advised.

Why Families Choose Asian Navkar Hospital, Indore

  • Fertility, embryology, high-risk obstetrics and a Level 3 NICU in one hospital, so care continues after a positive pregnancy test.
  • Senior IVF team with 30+ years of clinical experience, including clinical embryologists.
  • Counselling for both partners, transparent written estimates and cashless TPA/insurance desk support where policies allow.

Related Services

Medical References

This page is for general information and does not replace a consultation. Treatment decisions are made only after an in-person evaluation by a qualified doctor at Asian Navkar Hospital, Indore.

Translocation Screening
Identifies structural chromosomal imbalances in embryos.
Reduces Miscarriage Risk
Helps avoid transfer of embryos with unbalanced structure.
Supports Carrier Couples
Designed for known chromosomal rearrangement carriers.
Combined With IVF
Performed as part of your IVF/ICSI treatment cycle.

Is this for you?

✓ Known chromosomal translocation carrier ✓ Recurrent miscarriage with a carrier parent ✓ Previous child with chromosomal imbalance ✓ Family history of structural rearrangements

How We Treat PGT-SR (Structural Rearrangement Testing)

1
Genetic Counselling
Reviewing your specific chromosomal rearrangement.
2
Embryo Culture & Biopsy
Embryos are grown and a small sample is taken.
3
Structural Analysis
Cells are analyzed for balanced or unbalanced chromosome structure.
4
Selective Transfer
Balanced embryos are prioritized for transfer.

Frequently Asked Questions

Not always. It may reduce miscarriage risk but involves IVF. Natural conception with prenatal testing is also a valid option.

Both partners are usually karyotyped to identify who carries the rearrangement.

Many tests cannot reliably tell a balanced carrier embryo from a fully normal one; both are generally suitable for transfer.

It varies with the type of rearrangement; often a significant proportion are unbalanced, so more embryos help.

It is strongly recommended before deciding.

Dr. Vedant Jain
Dr. Vedant Jain
MBBS, MS (Obs & Gynae), DNB • Consultant IVF Specialist, Gynecologist & Embryologist
Reg. No. MP-37997 (MP Medical Council)

Dr. Vedant Jain is an IVF Consultant, Gynecologist, and Certified Embryologist at Asian Navkar Hospital, Indore. Holding post-graduate degrees including an MS and DNB in Obstetrics and Gynecology, he practises reproductive medicine at Asian Navkar Hospital. Dr. Jain specializes in advanced Assisted Reproductive Technologies (ART), complex infertility assessments, low AMH (ovarian reserve) optimization, and fertility preservation. By combining clinical gynecology with laboratory embryology, he works with couples who have had unsuccessful IVF cycles to plan further evaluation and treatment.

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