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PGT Testing in Indore: Preimplantation Genetic Testing

PGT tests IVF embryos for chromosome problems or a known inherited disease before transfer. Compare PGT-A, PGT-M and PGT-SR, their benefits, limits and rules.

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Preimplantation genetic testing (PGT) checks embryos created through IVF for specific genetic or chromosomal problems before one is transferred to the uterus. It can help couples who carry an inherited disease or a chromosomal rearrangement to have a baby unaffected by that condition. At Asian Navkar Hospital, Indore, PGT is offered after genetic counselling and only for medical reasons; sex selection is illegal and is never performed.

Types of PGT

  • PGT-A – screens for an abnormal number of chromosomes (aneuploidy)
  • PGT-M – tests for a specific single-gene disorder known in the family, such as thalassaemia
  • PGT-SR – for couples where one partner carries a chromosomal translocation or inversion

How PGT Is Done

  1. IVF with ICSI creates embryos.
  2. On day 5–6, a few cells are gently removed from the outer layer (trophectoderm) of each blastocyst.
  3. Embryos are frozen while the biopsy is analysed in a genetics laboratory.
  4. An embryo reported as unaffected is transferred in a later frozen cycle.

Limitations You Should Know

PGT does not test for every possible condition, results can occasionally be inconclusive or mosaic, and testing does not replace pregnancy screening tests. Some embryos may not survive biopsy and freezing. For PGT-A in particular, benefit for routine IVF patients has not been proven. A prenatal test (such as CVS or amniocentesis) may still be advised during pregnancy.

Why Families Choose Asian Navkar Hospital, Indore

  • Fertility, embryology, high-risk obstetrics and a Level 3 NICU in one hospital, so care continues after a positive pregnancy test.
  • Senior IVF team with 30+ years of clinical experience, including clinical embryologists.
  • Counselling for both partners, transparent written estimates and cashless TPA/insurance desk support where policies allow.

Related Services

Medical References

This page is for general information and does not replace a consultation. Treatment decisions are made only after an in-person evaluation by a qualified doctor at Asian Navkar Hospital, Indore.

Embryo Health Screening
Identifies chromosomal or genetic abnormalities before transfer.
Reduces Miscarriage Risk
Helps select embryos with the best implantation potential.
Multiple Testing Types
Includes PGT-A, PGT-M and PGT-SR based on individual need.
Informed Family Planning
Supports couples with known genetic conditions in their family.

Is this for you?

✓ Advanced maternal age ✓ Recurrent miscarriage ✓ Known genetic condition in the family ✓ Previous failed IVF cycles ✓ Chromosomal translocation carriers

How We Treat Preimplantation Genetic Testing (PGT)

1
Embryo Culture
Embryos are grown to the blastocyst stage in the lab.
2
Embryo Biopsy
A few cells are carefully removed for testing.
3
Genetic Analysis
Cells are analyzed in a specialized genetics laboratory.
4
Informed Transfer
Only embryos with normal results are selected for transfer.

Frequently Asked Questions

PGT may technically detect sex chromosomes, but using it to select sex is a criminal offence under the PC-PNDT Act, and this information is never disclosed.

No. It reduces the risk of the specific condition tested but cannot rule out every problem.

Biopsy at the blastocyst stage is widely used and considered safe when performed by experienced embryologists.

Couples who carry a known single-gene disorder, such as both partners being thalassaemia carriers.

Yes, counselling before PGT is essential to understand the test, its accuracy and alternatives.

Dr. Vedant Jain
Dr. Vedant Jain
MBBS, MS (Obs & Gynae), DNB • Consultant IVF Specialist, Gynecologist & Embryologist
Reg. No. MP-37997 (MP Medical Council)

Dr. Vedant Jain is an IVF Consultant, Gynecologist, and Certified Embryologist at Asian Navkar Hospital, Indore. Holding post-graduate degrees including an MS and DNB in Obstetrics and Gynecology, he practises reproductive medicine at Asian Navkar Hospital. Dr. Jain specializes in advanced Assisted Reproductive Technologies (ART), complex infertility assessments, low AMH (ovarian reserve) optimization, and fertility preservation. By combining clinical gynecology with laboratory embryology, he works with couples who have had unsuccessful IVF cycles to plan further evaluation and treatment.

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